Dermal Corrosivity Testing Using the DermaSafe SCT™
A rapid, shelf-stable in chemico test kit for classifying skin corrosion. No animals required.
Buy DermaSafe
OECD 496OptiSafe EIT™ Main Assay
OECD 496 Validated · 90%+ Accuracy
The gold-standard human relevant, nonanimal product eye irritancy test. Shelf-stable, vegan, human tear chemistry, delivers results in <24 hours. Identifies ocular nonirritants and corrosives with the highest sensitivity of any NAM. Each kit tests 3 samples.
- 100% sensitivity; zero false negatives for nonirritants
- No aseptic technique required
- Validated with international regulatory acceptance
- Kit tests 3 samples
SCU #OSMA2796
IVD EITIVD EIT™ Main Kit
Full GHS Classification · NC → Cat 1
The only nonanimal test able to discriminate "Eye Protection Required" from no labeling required. Covers the full product spectrum, cosmetics to strong industrial solvents. Highest mechanistic relevance for ocular drug studies.
- Discriminates all 4 GHS eye categories (NC, 2B, 2A, 1)
- Uses food-source animal eyes; qualifies as nonanimal
- >90% accuracy per GHS classification
- Requires IVD Viability or TUNEL kit (sold separately)
SCU #IVDM3544
DermaSafeDermaSafe SCT™ High-Throughput
GHS 1A · 1B+1C · Not Corrosive · DOT Packing
Rapid in chemico skin corrosion test for classifying dermal corrosives. Supports GHS Category 1A / 1B+1C / Not Corrosive and DOT packing group assignment. Shelf-stable, no animals, high-throughput plate reader format.
- GHS 1A / 1B+1C / Not Corrosive classification
- DOT packing group assignment
- Colorimetric plate reader, high-throughput format
- Results in under 6 hours at room temperature
DSHT2903
Test Kit Categories
OECD TG 496 Validated
The OptiSafe Ocular Irritation Test (OECD 496)
- Kit Formats Pretest Kit guides assay selection; Main Assay and Surfactant Assay each cover 3 articles; H Kit and HMA Kit handle extreme acids and strong buffering materials
- How it works Best choice for eye area cosmetics and personal care. Add test material to shelf-stable vegan matrix, incubate overnight (18 h), read absorbance on spectrophotometer
- Output OD ratio applied to decision tree assigns GHS NC or refers for further testing, reported in under 24 hours
- Why it matters 100% sensitivity (zero false negatives), OECD TG 496 accepted internationally, no animals, no cell culture, no aseptic technique
Full GHS NC → Cat 1
The In Vitro Depth of Injury (IVD) Eye Irritation Test (IVD EIT)
- Kit Choices Dosing Kit; Viability Kit captures metabolic depth-of-injury; TUNEL Kit measures direct cell death
- How it works Apply material to food-source tissue, rinse with tear solution, incubate, measure depth of injury signal across corneal depth layers
- Classification Depth-dependent viability profile assigns GHS NC, 2B, 2A, and Cat 1 with >90% accuracy per category
- Unmet need Best choice for sunscreens and eyeshadows, mechanistic studies, and ophthalmic products and second opinions when there are suspicious results from other test methods. Only in vitro method to correctly discriminate GHS 2B vs. 2A; ensures labeling is precise and users are accurately warned when eye protection is required.
Skin Corrosion · DOT Packing
The DermaSafe Skin Corrosion Test (DermaSafe SCT™)
- Two formats High-throughput plate reader kit for the lab; Field Test kit for visual read on-site. Both use the same in chemico skin biomarker.
- How it works Add test material to biomarker tube, incubate at room temperature, add colorimetric reagent, and read absorbance or assess color visually.
- Regulatory output Classifies GHS 1A, 1B+1C, and Not Corrosive; assigns DOT packing groups I, II+III, and IV for transport compliance.
- Simplicity Room-temperature incubation, shelf stable, no animal tissue or cells, suitable for lab or field deployment.
Research Grade
Research Products
- Artificial Tear Solution Physiologically balanced human tear mimetic formulated to reduce false positive rates across a range of in vitro ocular safety tests
- Emergency Eyewash Research antioxidant and buffering defense wash solution.
- Viability Stain Kit Measures the metabolic (ATP) activity signature in fixed tissue; with consistent, reproducible staining
- TUNEL Kit Complete kit for identifying fragmented nuclei as a marker of cell death in fixed tissue; remarkably high signal-to-noise ratio for precise, publication-quality results
Contract Testing Services
Interested in OptiSafe EIT™, IVD EIT™ or DermaSafe SCT™ testing services rather than kits? Submit samples directly to our affiliate lab for GHS classification reports and regulatory data.
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